This article analyzes the phonetic similarity of the Uzbek and Karakalpak languages, their specific differences. Although these two languages belong to the same Turkic language family, they are distinguished from each other by their specific phonetic systems. The article provides a comparative analysis of the number of vowel and consonant phonemes in both languages, stress and pronunciation rules, differences and commonalities in phonetic changes in word structure. The results of our research provide an opportunity for a scientific analysis of the differences and similarities of these two languages