This article studies an infinite-server queue in a Markov environment, that is, an infinite-server queue with arrival rates and service times depending on the state of a Markovian background process. Scaling the arrival rates (i) by a factor N and the rates (ij) of the background process by N1+E (for some E>0), the focus is on the tail probabilities of the number of customers in the system, in the asymptotic regime that N tends to . In particular, it is shown that the logarithmic asymptotics correspond to those of a Poisson distribution with an appropriate mean