Brown, Benedict

Declercq, Jeroen

Hauspie, Stijn

Martens, Ann

Oosterlinck, Maarten

Saunders, Jimmy

Van Gool, Luc

English

Ghent University Academic Bibliography

Quantitative assessment of articular cartilage degeneration of the metacarpal condyle using a 3D scanning system Declercq J.*1, Brown B.2, Oosterlinck M. 1, Van Gool L. 2 , Hauspie S3., Saunders J.3, Martens A.* 1 Faculty of Veterinary Medicine 1, Department of Medical Imaging of Domestic Animals3 Ghent University, Belgium, Faculty of Engineering, Leuven University 2, Belgium Introduction Staining cartilage surfaces with Indian ink is used to detect surface fibrillation and proteoglycan depletion. Brommer et al. (2003) developed the Cartilage Degeneration Index (CDI) as a quantitative measurement for cartilage degeneration over the entire proximal articular surface of the proximal phalanx (P1). The goal of the present study was to obtain a CDI for the articular cartilage of the metacarpal condyle (MC3) using a novel 3D scanning technique. Materials and Methods welve fetlock joints, 6 from young (3 years old) and 6 from older (20 to 25 years) Warmblood horses, were harvested immediately after slaughter. A stereo triangulation scanner was used to acquire full 3D models before and after staining. P1 and the MC3 were mounted vertically in a clamp on a computer-controlled turntable. Scans were made at 5 degree intervals and were automatically assembled. Consecutively, the operator selected the cartilage region using a paintbrush metaphor and the surface area of the selected cartilage was measured based on the 3D geometry. Each manual selection was repeated 5 times. Based on the average ratio between stained and unstained gray values, the CDI (i.e. percentage of darkening) was calculated. Differences in surface area and CDI between the younger and older horses and between P1 and MC3 were analyzed using a GLM procedure for repeated measurements (SPSS 17.0; α= 0.05). Results CDIs ranged from 10.72 to 36.31%. CVs of CDI were below 2%. There was no significant difference between the repeated measurements for surface area and CDI (P = 0.421 and 0.098, respectively). No significant difference was seen between younger and older horses for surface area and CDI (P = 0.915 and 0.842 respectively). The CDI of P1 and MC3 were not significantly different (P = 0.249). Conclusion This novel 3D scanning system allowed the calculation of CDI values of the distal metacarpal condyle, an area previously left unexplored because of the complex geometry of this region. Further research is now possible to elucidate the cartilage status of the metacarpal condyle in sound and diseased horses.  ECVS	  proceedings	  2011	  69	  large	  animal	  session	  	  

Quantitative assesment of articular cartilage degeneration of the metacarpal condyle using a 3D scanning system

https://biblio.ugent.be/publication/2047926/file/2051055

Quantitative assesment of articular cartilage degeneration of the metacarpal condyle using a 3D scanning system

Abstract

Similar works

Full text

Available Versions

Ghent University Academic Bibliography