Amphiphilic phthalocyanine-cyclodextrin conjugates for cancer photodynamic therapy

Abstract

Three phthalocyanines (Pcs) conjugated with alpha-, beta- and gamma-cyclodextrins (CDs) were prepared and their application as photosensitizer (PS) agents was assessed by photophysical, photochemical and in vitro photobiological studies. The photoactivity of Pc-alpha-CD and Pc-gamma-CD ensures their potential as PDT drugs against UM-UC-3 human bladder cancer cells

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