The demand for business-to-business (b-to-b) Living Lab projects is growing significantly within iMinds Living Labs. Real-life experimentation is a key requirement for Living Labs as it enables deeper insights in the potential success of the innovation. However, literature has not provided insights on whether the Living Lab methodology is an appropriate approach for real-life experimentation with b-to-b innovations and does not provide conditions where experimenting in b-to-b Living Lab projects is applicable. Within this paper we performed a cross-case analysis of eight b-to-b Living Lab cases. We conclude that real-life experimentation is possible in Living Lab projects but the possibilities vary on a case level. Three barriers have been identified that help to determine the possibility of real-life experimentation in a b-to-b Living Lab project: the technological complexity, the need for integration and the difficulty to identify testers. Finally, we also described how these blocking factors can be overcome. This can be interesting for the reader to identify whether real-life experimentation will be possible or not in a b-to-b context
