Tan, Wen Siang

Universiti Putra Malaysia Institutional Repository

Universiti Putra MalaysiaNDPath™-A Simple Solution To Newcastle Disease Virus PathotypingThe Newcastle disease virus (NOV) is an economically important poultry virusworldwide which also infects many types of birds. Although this virus is con-trolled effectively by vaccination and mass slaughtering, sporadic outbreaks still occur.Various kinds of tests have been developed to distinguish the different strains of NOV.Unfortunately, these tests are often laboratory specific, expensive or tedious and theywere not able to distinguish between the vaccine strains(mesogenic and lentogenic strains) and the field isolates (ve-logenic strains) which are the etiologic agents for the disease.We have developed a novel peptide that can distinguish be-tween vaccinated chickens and those that were infected withthe field isolates of NOV.It is found that this form of NOV typing is not previously re-ported, and furthermore it is the first invention that can distin-guish the velogenic from the mesogenic strains. This inventionis therefore useful as a routine diagnostic test to locate the NDPath™source of an epidemic. In addition, this peptide is able to in-hibit the replication of the virus and may be used as an antiviral drug.NOPath™is a patent-pending (PI20013687) invention.For further information, kindly contact:Assoc. Prof. Dr. Tan Wen SiangDepartment of MicrobiologyFaculty of Biotechnology and Biomolecular SciencesUniversiti Putra Malaysia43400 UPM. Serdang, SelangorMalaysiaTel: +60389466715Fax: +603 8943 09 J 3E-mail: wstan@fsas.upm.edu.my26

NDPath™ - a simple solution to newcastle disease virus pathotyping

http://psasir.upm.edu.my/51826/1/NDPath%E2%84%A2-A%20simple%20solution%20to%20Newcastle%20disease%20virus%20pathotyping.pdf

NDPath™ - a simple solution to newcastle disease virus pathotyping

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Universiti Putra Malaysia Institutional Repository