The present study indicates that the only portal of
entry of A . hydrophila serovar I isolate V which induces
EUS - l ike lesions in C. batrach us is the intramuscular
injection and the effective dose is 6 .5 X 1 0 6 CFU / fish . The
lesions do not develop into putrefied necrotic ulcers but
heals gradually within 14 - 18 days of initial injection .
Immersion exposure and oral administration of A . hydrophila
serovar I isolate V were incapable of inducing EUS - like
lesions in C . batrachus .Intramuscular injection of A . hydrophila serovar I
strain V cause severe pathological changes in C . batrachus ,
only at the site of injection and did not produce systemic infection . Clarias batrachus mounts a strong inflammatory
response against A.hydrophila following intramuscular
infection and is capable of eliminating bacteria from the
infected tissue s and efficient in fast wound healing and
repair of the dermal lesions
