Data on antioxidant, hypolipidemic and hepatoprotective potential of (Benn.) Benth leaves.

Abstract

This data article reports on the biochemical activity of ethanolic extract of (Benn.) Benth leaves (ETD) in male Wistar rats at an oral dose of 500-1500 mg/kg daily for 14 days. Control groups were administered distilled water and Vitamin C (10 mg/kg; b.wt). Indices of oxidative stress, dyslipidemia, liver injury and liver pathology were estimated in the plasma and organs after the investigation period. Oral treatment with ETD increased organ superoxide dismutase (SOD) activity, renal reduced glutathione (GSH) and plasma high density lipoprotein (HDL) concentrations while reducing plasma alanine transaminase (ALT) activity, plasma cholesterol (CHOL), bilirubin (DBIL) and organ malondialdehyde (MDA) concentrations (<0.05). Data was supported by histological report showing no pathologic abnormality. This data indicate ethanolic extract of leaves shows antioxidant, hypolipidemic and hepatoprotective potential