Vascular reactivity of conduit arteries is not altered in patients with ulcerative colitis and metabolic syndrome.

Abstract

Aim of this study was firstly to clarify, in a large group of patients, whether endothelial function of conduit arteries is affected by UC. Secondly, to investigate whether MS in patients with UC has an impact on the endothelial function. Among the patients with UC, twenty-three were also affected by MS, whereas twenty-two patients with MS were present in the control group. FMD was similar in patients with UC and controls (11.8±0.9% and 12.2±0.8, respectively, p=NS). While the presence of MS in the control group was associated with impairment of endothelial function (13.6±0.8% in healthy controls and 10.2±0.6 in patients with MS, p=0.003), patients with MS and UC did not show any worsening of their endothelial function (11.4±1.0% in patients with UC and SM and 12.1±1.3 in patients with UC without MS; p=0.35). NMD was similar in all the groups

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