We propose to create a medical imaging artificial intelligence (AI) center (name: Pittsburgh Center for Artificial Intelligence Innovation in Medical Imaging). AI is the new revolutionary technique for medical research and is reshaping tomorrow’s clinical practice in medical imaging (radiology and pathology). Our long-term vision is to build a center for innovative AI in clinical translational medical imaging by combining computational expertise and clinical resources across Pitt, UPMC, and CMU. The Center concept is a formalization of a group of researchers and clinicians that are united by the common theme: “building advanced and trustworthy imaging AI for clinical applications.” Our short-term plan is to assemble dedicated members from the School of Medicine, the School of Engineering, and the School of Computing and Information. We seek a Scaling grant from the Momentum Funds to foster collaborative activities of the Center between these three Pitt schools to provide the essential components of a competitive P41 (Biomedical Technology Resource Centers) center grant in 2 years. The National Institute of Biomedical Imaging and Bioengineering (NIBIB) P41 mechanism aligns with the overall vision of this initiative to develop specific AI imaging tools and to support the dissemination and commercialization pathways that are essential to bringing AI imaging tools to clinical practice. These projects will include key components: 1) Clinical need-driven medical imaging AI development and evaluation of tools, models, systems, and informatics, 2) Core imaging AI theory, methodology, and algorithm investigation, and 3) Linking imaging phenotypes to the biological (genomics and proteomics) underpinnings. To date, we have already 35 members for the Center. The Pitt Momentum Funds will provide critical scaling support to promote communication between the three Pitt schools to develop a competitive P41 grant application and a sustainable framework to ensure the clinical impact of these AI imaging tools
