A study was carried out on pesticide residues in Italian wines from vineyards with a known history, where treatments were applied according to good agricultural practice. The investigation concerned 64 wine samples from 6 Italian regions and 31 active ingredients (a.i.) representing the most widely used fungicides and insecticides in Italian viticulture. Residues of 5 a.i. were detected but at very low concentrations: benomyl (0.05 ppm), dimethoate (0.02-0.06 ppm), iprodione (0.02-0.07 ppm), metalaxyl (0.04-0.14 ppm), and vinclozolin (0.02 ppm). Relationships between pesticide treatments and residues are discussed and the presence of residues is correlated to the characteristics of the a.i