PURPOSE: To evaluate the long-term outcomes of laser in situ keratomileusis (LASIK) for high
myopia with or without astigmatism.
SETTING: Vissum Instituto Oftalmologico de Alicante and Miguel Hernandez University, Alicante,
Spain.
DESIGN: Retrospective–prospective case series.
METHODS: Laser in situ keratomileusis was performed using the Visx 20/20 excimer laser. The
minimum follow-up was 15 years. The main outcome measures were uncorrected (UDVA) and
corrected (CDVA) distance visual acuities, manifest refraction, and corneal topography.
RESULTS: This study included 40 patients (40 eyes) with a mean age of 51.08 years G 6.67 (SD)
(range 41 to 60 years) with high myopia ( 6.00 to 18.00 diopters [D]). At 15 years, the safety index
was 1.23 and the efficacy index, 0.95. During the follow-up, a significant increase in the dioptric
power of all keratometric variables was detected (P%.028, Friedman test), the most notable
increase occurring between 3 months and 1 year (P%.005). At 15 years
