Studies on the biosynthesis of syringomycin E and syringopeptin 22A

Abstract

Feeding radioactive putative precursors to the bacterial cultures of Pseudomonas syingae pv. syringae in the presence of a protein synthesis inhibitor allowed the formation of radiolabelled syringomycin and syringopeptin. The result indicates that a nonribosomal mechanism of peptide synthesis is operating in the formation of these peptide metabolites

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