The syringopeptins (SPs) are antimicrobial cyclic lipodepsipeptides produced by several plant-associated pseudomonads. A novel SP, SP508, produced by the apple colonizing bacteria, Pseudomonas syringae pv. lachrymans, is different from other SPs by having three instead of four α,β unsaturated amiino acids. The antimycobacterial activity of SPs is also evidenced for the first time