Attuale:PATHOLOGICA, OSPEDALI GALLIERA, VIA MURA DELLE CAPPUCCINE, 14, GENOA, ITALY
Pacini Editore Srl:via A Gherardesca 1, I 5I6121 Ospedaletto Pisa Italy:011 39 050 3130240, EMAIL: [email protected], INTERNET: http://www.pacinieditore.it, Fax: 011 39 050 3130300
Abstract
Cholestasis is frequently encountered in human liver transplants. In a series of 82 liver fine-needle aspiration biopsies performed in 20 grafted patients, the incidence rate of cholestasis was 55%. Cholestasis may predominantly be localized in the hepatocyte cytoplasm, or in the biliary tree or in both sites. In our cases it was most frequently associated with acute rejection (53%), followed by preservation injuries (29%) and ciclosporin toxicity (12%), respectively. The severity and the chronologic distribution of cholestatic episodes seem to vary according to the other associated pathologic conditions
