Acta Neurologica:Piazza S Pasquale A Chiaia 10, 80121 Naples Italy:011 39 81 7463103
Abstract
The daily changes of plasma free and total tryptophan were studied in 15 healthy volunteers. Six blood samples were taken for each subject. A method involving pH control was used. The results show that plasma free tryptophan concentrations progressively rise to reach a peak at 3.30 hr. The total tryptophan concentration reaches a peak at midnight