Secondary or pathologic fractures, associated with osteosarcoma, have been
considered for a long time to be a negative prognosis regarding its evolution in
the patients. The aim of this study was to evaluate the prognostic importance of
such pathologic fractures in osteosarcoma patients receiving new therapies as
well as the best conditions for surgery aiming at "limbs salvage". On a total of
22 patients affected by osteosarcoma, we performed a retrospective study with 12
patients showing pathologic fractures caused by osteosarcoma and 10 patients
without any pathologic fracture. The patients enrolled into Timisoara University
Hospital have been followed up along 5 years or until a reappearance of either
the disease or metastases, distant or loca
