Sources of cadmium exposure in an Italian population: a cross-sectional study

BOTTECCHI, ILIARIA

Castiglia, P

Cherubini, A

FILIPPINI, TOMMASO

Greco, S

Krogh, V

Maffeis, G

MALAGOLI, Carlotta

MALAVOLTI, Marcella

Michalke, B

Modenesi, M

Sieri, S

Vescovi, L

VINCETI, Marco

English

Archivio istituzionale della ricerca - Università di Modena e Reggio Emilia

1 ICS 2015     International  Cadmium Symposium 2015        ICS 2015 Congress Proceedings   	-27, 2015   46 P-1 _ SOURCES OF CADMIUM EXPOSURE IN AN ITALIAN POPULATION: A CROSS-SECTIONAL STUDY  Filippini Tommaso1, Cherubini Andrea2, Greco Salvatore2, Maffeis Giuseppe2, Malagoli Carlotta1, Bottecchi Ilaria1, Malavolti Marcella1, Sieri Sabina3, Krogh Vittorio3, Vescovi Luciano4, Modenesi Marina4, Castiglia Paolo5, Michalke Bernard6, Vinceti Marco1  1Environmental, Genetic and Nutritional Epidemiology Research Center (CREAGEN), Department of Diagnostic, Clinical and Public Health Medicine, University of Modena and Reggio Emilia, Reggio Emilia, Italy 2Italy TerrAria srl, Milan, Italy 3Epidemiology and Prevention Unit, Fondazione IRCCS Istituto Nazionale dei Tumori Milan, Italy 4IREN, Reggio Emilia and Piacenza, Italy 5Department of Biomedical Sciences, Hygiene and Preventive Medicine Unit, University of Sassari – AOU Sassari, Sassari, Italy 6Research Unit Analytical BioGeoChemistry, Helmholtz Zentrum München – German Research Center for Environmental Health GmbH, Munich, Germany   Main sources of Cadmium (Cd) exposure in the human are food and cigarette smoking as, but also outdoor and indoor air pollution can be important, mainly from industrial emissions, fossil fuel combustion and solid waste incineration. The aim of this study was to assess the influence of outdoor air pollution on serum Cd levels in fifty residents randomly selected from the municipal population of Modena, Northern Italy. We geocoded the current residence of these subjects and modeled their outdoor ambient air 	  	  (PM10), with the CAlifornia LINE Source Dispersion Model version 4 (CALINE-4), as a proxy of environmental air Cd. Information on smoking habits and Cd  dietary intake were also collected, to assess these two additional sources of exposure. We used both crude and multivariate linear regression models to determine the influence of outdoor PM10 levels, smoking and dietary Cd intake on serum Cd. Median values (25th–75th) for serum and dietary Cd were 40.85 ng/l (30.05-53.50) and 13.36 μg/die (10.45-  -coefficients were 0.617 (95% CI -0.194–1.428, P=0.133), 0.026 (-0.827–0.829, P=0.952) and 6.962 (-0.022–13.945, P=0.051) for PM10, diet and smoking, respectively. Corresponding adjusted values were 0.463 (-0.365–1.292, P=0.266), -0.036 (-0.866–0.793, P=0.930) and 6.057 (-1.175–13.289, P=0.099), respectively. In our population, the most important factor influencing Cd serum content thus appears to be cigarette smoking, followed by outdoor air pollution and lastly by diet.    

https://iris.unimore.it/bitstream/11380/1069869/2/abs_09_CDSYM2015poster_filippini.pdf

Sources of cadmium exposure in an Italian population: a cross-sectional study

Abstract

Similar works

Full text

Available Versions

Archivio istituzionale della ricerca - Università di Modena e Reggio Emilia