Migrena je česta primarna glavobolja koja se češće javlja u žena nego u muškaraca, s omjerom 3 : 1 i procijenjenom jednogodišnjom prevalencijom od približno 15 % u općoj populaciji, pretežno u generativnom razdoblju. Osim što se češće javlja u žena, migrena na njih ima i snažniji utjecaj u usporedbi s muškarcima. Perimenstrualni migrenski napadaji karakterizirani su jačim intenzitetom boli i duljim trajanjem u odnosu na ostale vrste napadaja. Zbog hormonskih fluktuacija tijekom perimenopauze kod žena koje su prethodno imale perimenstrualne napadaje često dolazi do pogoršanja migrene. Migrena je također povezana s ozbiljnim vaskularnim bolestima te predstavlja jedan od najčešćih nekonvencionalnih čimbenika rizika za nastanak moždanog udara u mladih žena. Osim toga, migrena ima značajan utjecaj na radnu sposobnost, kao i na neplaćene sate, slobodno vrijeme i općenito smanjuje kvalitetu života. Također, ima izražen utjecaj na obiteljski život.Migraines are a common primary headache that occur more frequently in women than in men. They have a ratio of 3:1 and a predictable one-year prevalence of circa 15% in the general population, for the most part in the reproductive period. In addition to occurring more often in women, migraines also have a greater bearing on women over men. Perimenstrual migraine attacks are typified by deeper pain intensity and duration compared to other types of attacks. Due to hormonal fluctuations in perimenopause, migraines are often graver in women who previously suffered from perimenstrual attacks. They are also associated with serious vascular diseases and are one of the most common non-conventional risk factors for stroke in young women. Moreover, migraines have a significant impact on work capability, unpaid work hours and free time, and overall diminish the quality of life. They also have a noticeable impact on family life
