Glavni uzrok urogenitalne atrofije kod žena u menopauzi je gubitak estrogena. Genitourinarni sindrom menopauze uključuje vulvovaginalnu atrofiju i postmenopauzalne promjene donjega urinarnog trakta kao što su učestalost mokrenja, nikturija, žurnost, urinarna inkontinencija i infekcije mokraćnog sustava. Genitourinarni sindrom je kronično stanje sa simptomima koji se s vremenom pogoršavaju kod neliječenih žena. Atrofične promjene vulve, vagine i donjega urinarnog trakta mogu imati veliki utjecaj na kvalitetu života žena u postmenopauzi, a kliničari bi trebali ispravno identificirati obrazac promjena u genitourinarnom sindromu menopauze i liječiti ih na odgovarajući način.The major cause of urogenital atrophy in menopausal women is estrogen loss. The genitourinary syndrome of menopause includes vulvovaginal atrophy and postmenopausal changes of the lower urinary tract such as frequency, nocturia, urgency, urinary incontinence and urinary tract infections. Genitourinary syndrome is a chronic condition with symptoms deteriorating over time in untreated women. Atrophic changes of the vulva, vagina and lower urinary tract can have a large impact on quality of life in postmenopausal women, and clinicians should correctly identify the pattern of changes in genitourinary syndrome of menopause and manage them appropriately
