The hemodynamic effects of the ACE-inhibitor ramipril were evaluated in five
healthy horses. Ramipril, at a dose of 200 μg/kg was given per os for four days in each subject.
The heart rate and arterial blood pressure (systolic, diastolic and mean) were monitored one day
before and during the four days of treatment in each horse at specific time intervals. Compared
to pre-treatment values, significantly reduced arterial blood pressures were evidenced on each
day post-treatment starting from day 3. No difference of the heart rate values was found during
treatment
