The significant beneficial effect of treatment with immune checkpoint inhibitors is relatively often accompanied by adverse events, of which neurological events are rare but can be life-threatening.The article presents neurological complications of treatment with immune checkpoint inhibitors. Two given clinical cases describe neurological adverse events with a clinical picture of peripheral nervous system involvement, namely myositis and acute inflammatory demyelinating polyneuropathy.Pomembnemu ugodnemu učinku zdravljenja z zaviralci imunskih nadzornih točk so relativno pogosto pridruženi neželeni zapleti, med katerimi so nevrološki redki, a lahko življenje ogrožujoči.V prispevku so predstavljeni nevrološki zapleti zdravljenja zzaviralci imunskih nadzornih točk. Podana klinična primeraopišeta nevrološka zapleta s klinično sliko prizadetosti perifernega živčevja, in sicer miozitisom in akutno inflamatorno demielinizirajočo polinevropatijo
