Nowadays, with the salient advantages of the seawater desalination process, membrane distillation (MD) technology has received increased interests to achieve desalination application. As a heat-based technology, by using the hydrophobic membrane, MD provides high efficiency in the desalination process of seawater, RO water and other solutes with high concentrations of dissolved solids. Besides, this is an alternative technology to significantly reduce the environmental impacts of traditional desalination technologies commonly used, such as distillation or reverse osmosis. In many factors affecting the desalination capacity of the membrane distillation system, membrane module configuration has a strong influence in evaluating the economic and technical efficiency of the technology. This review aims to assess the suitability of MD technology under different perspectives on the current types of membrane module configurations that include flat sheet, tubular, hollow fibre and spiral wound membranes. In addition, the evaluation of the advantages and disadvantages of the membrane module configurations will guide further studies to improve the shortcomings of existing MD technologies
