Barceló, D.

Huerta, B.

León-León, V.M. (Víctor Manuel)

Moreno-González, R. (Rubén)

Rodríguez-Mozaz, S.

English

Moreno-González, Rubén

Rodríguez-Mozaz, Sara

Huerta, Belinda

Barceló, Damià

León, Víctor Manuel

Digital.CSIC

Bioaccumulation of pharmaceuticals in moluscs and fishes from a Mediterranean coastal lagoon (Mar Menor SE Spain)

Rodríguez-Mozaz, S. (Sara)

Huerta, B. (Belinda)

Barceló, D. (Damià)

León, V.M. (Víctor Manuel)

Repositorio Institucional Digital del IEO

                             Book of Abstracts submitted to the IV Congress of Marine Sciences. Las Palmas de Gran Canaria, June 11th to 13th          Title: Book of Abstracts submitted to the IV Congress of Marine Sciences. Las Palmasde Gran Canaria, June 11th to 13th. 488 pp.ISBN - 10: 84-697-0471-0ISBN - 13: 978-84-697-0471-4Poster’s AbstractsBioaccumulation of pharmaceuticals in moluscs and fishes from a Mediterranean coastal lagoon(Mar Menor SE Spain)Moreno-Gonza´lez, R.1, Rodrı´guez-Mozaz, S.2, Huerta, B.2, Barcelo´, D.2,3, Leo´n, V.M.11Instituto Espan˜ol de Oceanografı´a, Centro Oceanogra´fico de Murcia, Apdo. 22, C/ Varadero 1, 30740San Pedro del Pinatar, Murcia, Spain2Catalan Institute for Water Research (ICRA) - Parc Cientı´fic i Tecnolo`gic de la Universitat de Girona,Edifici H2O. Emili Grahit ,101- 17003 Girona , Spain3Department of Environmental Chemistry, IDAEA-CSIC, C/Jordi Girona 18-26, 08034 Barcelona, SpainAbstractThe use of pharmaceuticals is increasing every year for human and veterinary applications, and con-sequently their occurrence in the environment is being confirmed in many environmental matrices inthe last decades. Not only few data are available about their presence in the marine environment butalso bioaccumulation and seasonal variations on wild biota in marine ecosystems are rather sparse. Inthis study 20 pharmaceuticals (β-blockers, psychiatric drugs, analgesics/anti-inflammatories, antiplateletagent, diuretic, to treat asthma and antihelmintic) were analyzed in fishes and molluscs from the MarMenor lagoon (SE Spain). The fish species considered were golden grey mullet (Liza aurata) and blackgoby (Gobius niger) meanwhile the mollusc species were cockle (Cerastodema glaucum), noble penshell (Pinna nobilis) and sea snail (Murex trunculus). In golden grey mullet two matrices were consid-ered, muscle and liver, however whole body was used in the rest of species. Their spatial distributionthroughout this lagoon was characterized considering 9 sampling areas and two different sampling pe-riods, spring and autumn in 2010. The extraction of pharmaceuticals from biota was carried out bypressurised liquid extraction (PLE) step prior to gel permeation chromatography (GPC). Ultra-high-performance liquid chromatography coupled to tandem mass spectrometry (UHPLC–MS/MS) was usedfor their analysis (Huerta et al., 2013).Under our knowledge this is the first study about pharmaceuticals in marine biota in Spanish seawaters.Eighteen pharmaceuticals were detected in muscle in golden grey mullet, eight ones in black goby (8analytes) and nine ones in molluscs. However less pharmaceuticals were detected in liver than in muscle.The highest concentration detected in golden grey mullet was reached by carbamazepine. In molluscsthe pharmaceuticals were detected at low ng g−1 reaching the highest concentration in sea snail.Seasonal variations were also assessed considering spring and autumn samples. Bioaccumulation factorsof pharmaceuticals from water and sediments were determined, and only in the case of sea snail biomag-nification factors from cockle were also estimated because cockle is the common prey of sea snail in thislagoon.Acknowledgement. This work has been supported by the Spanish Inter-Ministerial Science and Tech-nology Commission through ‘DECOMAR’ project (CICYT, CTM2008-01832) and by Seneca Founda-tion (Region of Murcia, Spain) through ‘BIOMARO’ project (15398/PI/10).ReferencesHuerta B, Jakimska A, Gros M, Rodriguez-Mozaz S, Barcelo´ D. Analysis of multi-class pharmaceuticals in fish tissues by ultra-high-performance liquid chromatography tandem mass spectrometry. J Chromatogr A 2013; 1288: 63-720.318 Wednesday, June 11th

http://www.repositorio.ieo.es/e-ieo/bitstream/10508/2432/1/BookofAbstracts%20Bioaccumulation%20of%20pharmaceuticals%20Seminario%20Quimica%20Marina%202014.pdf

Bioaccumulation of pharmaceuticals in moluscs and fishes from a Mediterranean coastal lagoon (Mar Menor SE Spain)

Abstract

Similar works

Full text

Available Versions

Digital.CSIC

Repositorio Institucional Digital del IEO