The purpose of this study is to establish the role to confer to diffusion weighted sequences
(DWI) in the detection of early stage of sacroileitis in patients with Crohn's Disease (CD)

, F. Midiri

, G. Lo Re

COSTANZO, Massimo

DI PIAZZA, Ambra

PICONE, Dario

RICCERI, Viola Maria

SALERNO, Sergio

SERRAINO, Salvatore

VERNUCCIO, Federica

Archivio istituzionale della ricerca - Università di Palermo

Page 1 of 7The role of DWI sequences in preclinical investigationsof the sacroiliac joints anomalies in patients with Crohn'sdisease. Our experiencePoster No.: C-0501Congress: ECR 2016Type: Educational ExhibitAuthors: M. Costanzo, A. Di Piazza, S. Serraino, F. Vernuccio, D. Picone,V. Ricceri, F. Midiri, S. Salerno, G. Lo Re; Palermo/ITKeywords: Small bowel, Gastrointestinal tract, Musculoskeletal joint, MR-Diffusion/Perfusion, MR, Imaging sequences, Colonography MR,Inflammation, PathologyDOI: 10.1594/ecr2016/C-0501Any information contained in this pdf file is automatically generated from digital materialsubmitted to EPOS by third parties in the form of scientific presentations. Referencesto any names, marks, products, or services of third parties or hypertext links to third-party sites or information are provided solely as a convenience to you and do not inany way constitute or imply ECR's endorsement, sponsorship or recommendation of thethird party, information, product or service. ECR is not responsible for the content ofthese pages and does not make any representations regarding the content or accuracyof material in this file.As per copyright regulations, any unauthorised use of the material or parts thereof aswell as commercial reproduction or multiple distribution by any traditional or electronicallybased reproduction/publication method ist strictly prohibited.You agree to defend, indemnify, and hold ECR harmless from and against any and allclaims, damages, costs, and expenses, including attorneys' fees, arising from or relatedto your use of these pages.Please note: Links to movies, ppt slideshows and any other multimedia files are notavailable in the pdf version of presentations.www.myESR.orgPage 2 of 7Learning objectivesThe purpose of this study is to establish the role to confer to diffusion weighted sequences(DWI) in the detection of early stage of sacroileitis in patients with Crohn's Disease (CD).Background0 false 14 18 pt 18 pt 0 0 false false falseDWI sequences, useful to recognize the inflammatory component of the wall and to get"qualitative" informations about the state of the disease, may also play a role to identifythe possible pathological involvement of the sacro-iliac joints in pre-clinical phase.Images for this section:Fig. 1: Initial signs of sacroiliitis in a patient with MC - fibrotic substenotic patternevaluation STIR coronal .© - Palermo/ITPage 3 of 7Findings and procedure detailsA slag free diet was followed by the patients during the three days before the examination;meantime, the previous day, a cathartic preparation, meaning the assumption of 4000 mlof water solution of polyethylene, was performed, in order to remove faecal rests and tosimplify the progression of the oral contrast agent.All patients with a positive histological data of CD were analyzed through colonoscopy.0 false 14 18 pt 18 pt 0 0 false false falseThe examination took approximately 40 minutes, being able to confirm the specificallytargeted sequences acquisition, during the ENTERO - RM, do not necessarily mean anyincrease of the duration of the whole examination.Conclusion0 false 14 18 pt 18 pt 0 0 false false falseOur experience suggests that DWI integration and ADC mapping, performed duringENTERO MRI study, in patients analyzed to follow up CD, provide important additionalinformations for the sacroileitis diagnosis, being able to explain any change in early stageof pathology.Images for this section:Page 4 of 7Fig. 2: Evaluation of the ADC maps in a patient with MC - fistulizing pattern inflammatoryand inflammatory signs of alteration of the sacroiliac joints , particularly on the right side .© - Palermo/ITPage 5 of 7Fig. 3: Evaluation of the ADC maps in a patient with MC to pattern - fibrotic and stenoticinitial signs of inflammatory alteration of the sacroiliac joints , particularly on the left side.© - Palermo/ITPage 6 of 7Personal informationReferences1. Kasper D, Fauci A, Longo D, BRaunwal E, Hauser S, Jameson J (2005).Harrison's Principi di Medicina Interna. McGraw Hill (2005); 2003-2016;2244-2248.2. Sheila L. Arvikar, Mark C. Fisher (2011); Inflammatory bowel diseaseassociated arthropathy. Curr rev Muscoloskelet Med (2011); 4: 123-131.3. John R. Leyendecker, Richard S. Bloomfeld, David J. DiSantis, GregoryS.Waters, Ryan Mott, Robert E. Bechtold; MR enterography in themanagement of patients with Crohn disease. Radiographics, volume 29, n. 6(2009).4. Matthew L Stoll, Ashish S Patel, Marilynn Punaro, Molly Dempsey-Robertson (2012); MR enterography to evaluate sub-clinical intestinalinflammation in children with spondyloarthritis. Pediatric Rheumatology2012; 10:6.5. Crohn BB, Ginzburg L, Oppenheimer GD (1932) Regional ileitis. Apathologic and clnical entity. JAMA 99: 132 3-96. Gore RM, Levine MS et al (2000) Textbook of gastrointestinal radiology. 2nded. Philadelphia, Pa: Saunders; 726-745.7. Goebell H, Wienbeck M, Schomerus H et al (1990) Evaluation of the Crohn'sDisease Activity Index (CDAI) and the Dutch Index for severity and activityof Crohn's disease. An analysis of the data from the European CooperativeCrohn's Disease Study. Med Klin 85: 573-576.8. Wills JS, Lobis IF, Denstman FJ (1997) Crohn disease: state of the art.Radiology 202: 597-610.9. Walsh DW, Bender GN, Timmons JH (1998) Comparison of ComputedTomography-Enteroclysis and traditional Computed Tomography in thesetting of suspected partial small bowel obstruction. Emerg Radiol 5: 29-37.10. Minordi LM, Vecchioli A, Poloni G, Bonomo L (2007) CT enteroclysis:multidetector technique (MDCT) versus single-detector technique (SDCT)in patients with spected small- bowel Crohn's disease. Radiol Med 112:1188-1200.11. Pupillo VA, Di Cesare E, Frieri G et al (2007). Assessment of inflammatoryactivity in Crohn's disease by means of dynamic contrast-enhanced MRI.Radiol Med 112: 798-809.12. Papanikolaou N., Grammatikakis J., Gourtsoyiannis (2004) Crohn's diseasemesenteric lympadnopathy wiht MR enteroclysis. ESAGR 2004: P-090.13. Horsthuis K., Stoker J. (2004) MRI-findings in patients with perianzi Crohn'sdisease. ESGAR 2004: P-011.14. Kaplan, Helms,Dussault, Anderson, Major; Risonanza Magneticadell'apparato locomotore; Verduci Ed.; 326-328.Page 7 of 715. Società Italiana di Reumatologia. Classificazione delle malattie reumaticheSIR. Reumatismo 1999;51:4-12.16. Taccari E, Spadaro A.; Reumatologia. In: Negri M, ed. Recentia in Medicina.Progressi II. Fisiopatologia e clinica diagnostica - Farmacoterapia. Torino:UTET 2005: 913-4317. Bozgeyik Z, Ozgocmen S, Kokacoc E; Role of Diffusion-Weighted MRI in thedetection of Early Active Sacroileitis. AJR2008; 191; 980-989.18. Colagrande S., Pallotta S., Vanzulli A., Napolitano M., Villari N. (2005)il parametro <<Diffusione>> in Risonanza Magnetica: elementi di fisica,tecnica e semeiotica. Radiol Med 109: 1-16.19. Colagrande S., Carbone S.F., Carusi L.M., Cova M., Villari N. (2006) Ilparametro "diffusione" in risonanza magnetica: le applicazioni in ambitoextra-neurologico. Radiol Med 111: 392-419.20. Oto A., Zhu F., Kulkarni K., Karzmar G., Turner J., Rubin D. (2009)Evalutation of Diffusion-weighted MR Imaging for Detection of BowelInflammation in Patients with Crohn's desease. Acad Radiol 16(5): 597-603.21. Broglia L., Gigante P., Papi C., Ferrari R., Gili L., Capurso L., Castrucci M.(2003) Enteroclisi con Risonanza Magnetica (ERM) nella malattia di Crohn.Radiol Med 106: 28-35.22. Baur A,Dietrich O, Reiser M; Diffusion weighted imaging of bone marrow:current status. European Radiology (2003); 13: 1699-1708.23. Ward R, Caruthers S, Yablon C, Blake M, DiMasi M, Eustace S: Analysis ofdiffusion changes in posttraumatic bone marrow using navigator-correcteddiffusion gradients. AJR (2000); 174; 731-734.24. Baur A, Stabler A, Brunig R et al: Diffusion weighted MRI of bone marrow;differentiation of benign versus pathologic compression fractures. Radiology(1998); 207: 349-356.

THE ROLE OF DWI SEQUENCES IN PRECLINICAL INVESTIGATIONS OF THE SACROILIAC JOINTS ANOMALIES IN PATIENTS WITH CROHN'S  DISEASE. OUR EXPERIENCE

https://iris.unipa.it/retrieve/handle/10447/172841/287577/ECR2016_C-0501.pdf

THE ROLE OF DWI SEQUENCES IN PRECLINICAL INVESTIGATIONS OF THE SACROILIAC JOINTS ANOMALIES IN PATIENTS WITH CROHN'S DISEASE. OUR EXPERIENCE

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Archivio istituzionale della ricerca - Università di Palermo