The Zombie Epidemic is a fun framework for investigating different scenarios of spreading disease. An extended Kermack - McKendrick model is analyzed. The only thing that can save humanity is to not get bitten or to find a remedy for the "zombie virus" (both almost impossible)

Tomczyk, Wojciech

Jagiellonian Univeristy Repository

21Zeszyty Naukowe Towarzystwa Doktorantów UJ Nauki Ścisłe, Nr 11 (2/2015)WOJCIECH TOMCZYK(Jagiellonian University)DO NOT LET THE DEAD BITE!  DIFFERENT SCENARIOS OF THE ZOMBIE  EPIDEMIC REEXAMINEDABSTRACTThe Zombie Epidemic is a fun framework for investigating different scenarios of spread-ing disease. An extended Kermack – McKendrick model is analyzed. The only thing that can save humanity is to not get bitten or to find a remedy for the ”zombie virus” (both almost impossible).KEYWORDSZombie, epidemic, Kermack – McKendrick model, ordinary differential equationsABOUT THE AUTHORWojciech TomczykMarian Smoluchowski Institute of Physics Jagiellonian University in Krakówe-mail: wojciech.tomczyk@doctoral.uj.edu.pl22Wojciech TomczykINTRODUCTIONZombies are fictional undead creatures (Figure 1), brought to life by magic1 or by a virus.2 Commonly found in horror and fantasy genre works,3 zombies have been regarded as mindless, reanimated human corpses feeding on human flesh.4 However, originally zombies are deeply rooted in tribal beliefs and rituals.5Figure 1. Zombie from the TV series “The Walking Dead”Source: http://amc.com/shows/the-walking-dead [accessed: 8.12.2015].1 W. Booth, Voodoo Science, “Science” 1988, No. 240, p. 274.2 D. Crisite, S. J. Lauro, Better Off Dead: The Evolution of the Zombie as Post-Human, New York 2011, p. 169.3 List of Zombies Films, [Online] https://en.wikipedia.org/wiki/List_of_zombie_films [accessed: 8.12.2015].4 M. Mogk, Everything You Ever Wanted to Know About Zombies, New York 2011, p. 214.5 E. B. Edmonds, M. A. Gonzalez, Caribbean Religious History: An Introduction, New York 2010, p. 111.23Do Not Let the Dead Bite! Different Scenarios of the Zombie...Recently the zombie subject has started to blossom in bio-mathematical science as a fairly good framework for simulating the spread of disease.6 Non- etheless, the main question stayed the same: can we withstand a zombie apo- calypse?7 What can happen and what shall people do to survive? In this work four possible scenarios based on the Kermack–McKendrick model8 will be described.MODELSFor the purpose of this article we will be considering six distinct classes:Susceptibles (S ) – human population,Infected (I) – those who carry a “zombie virus”,Zombies (Z) – those who lost an encounter with a zombie or were resur-rected,Quarantined (Q) – those under hospitalization,Removed (R) – those who died after an encounter with a zombie or perman- ently killed zombies (decapitation),Unaffected (U ) – those who are immune to the “zombie virus” forever.A relatively short timescale9 will be taken (up to 200 units of time regarded as days). Birth and background death rates are ignored. 6 D. Calderhead, M. Girolami, D. J. Higham, Is It Safe to Go Out Yet? Statistical Inference in a Zombie Outbreak Model, “Department of Mathematics and Statistics Re-search Report” 2010, No. 6, p. 1; P. Munz, I. Hudea, J. Imad, R. J. Smith, When Zombies Attack!: Mathematical Modelling of An Outbreak of Zombie Infection, [in:] Infectious Disease Modelling Research Progress, eds. J. M. Tchuenche, C. Chiyaka, Ottawa 2011; M. Crossley, M. Amos, SimZombie: A Case-Study in Agent-Based Simulation Construc-tion, “Agent and Multi-Agent Systems: Technologies and Applications Lecture Notes in Computer Science” 2011, No. 6682, p. 514; R. Smith?, Mathematical Modelling of Zombies, Ottawa 2013; A. A. Alemi, M. Bierbaum, C. R. Myers, J. P. Sethna, You Can Run, You Can Hide: The Epidemiology and Statistical Mechanics of Zombies, “Physical Review E” 2015, No. 92, p. 052801, DOI: PhyRevE.92.052801.7 T. C. Smith, Zombie Infections: Epidemiology, Treatment, and Prevention, “The British Medical Journal” 2015, No. 351:h6423, DOI: 10.1136/bmj.h6423.8 W. O. Kermack, A. G. McKendrick, A Contribution to the Mathematical Theory of Epidemics, “Proceedings of the Royal Society A: Mathematical, Physical and Engineer-ing Sciences” 1927, No. 115 (772), p. 700.9 Values of (S ), (I ), (Z ), (Q), (R) and (U ) are time dependent and their derivative over time will be marked by a dotted symbol, i.e. Ṡ ≡ dS / dt.24Wojciech TomczykSZRThe SZR model (Figure 2) is one of the simplest ones. Susceptibles, can beco-me zombies through transmission via an encounter with a zombie (transmission parameter β) and by being resurrected from the removed class (parameter ζ). Zombies can be moved to the removed class only by decapitation (parameter α).Figure 2. SZR modelSource: Own work.In overall, this model is described by three ordinary differential equations (ODEs):10Ṡ = –βSZ,Ż = βSZ + ζR – αSZ,                                (1)Ṙ = αSZ – ζR.10 G. Teschl, Ordinary Differential Equations and Dynamical Systems, “Graduate Studies in Mathematics” 2012, No. 140.25Do Not Let the Dead Bite! Different Scenarios of the Zombie...SIZRThe SIZR model (Figure 3) is an extension of the SZR model. In contradiction to the previous model, here we adopt a ”more realistic” scenario of a zombie outbreak where susceptibles are initially infected with a ”zombie virus” (latent infection which lasts 24 hours). In this scheme susceptibles move to an infected class and remain there for some period of time before becoming a zombie.Figure 3. SIZR modelSource: Own work.The time evolution is described by the following set of equations:Ṡ = –βSZ,İ = βSZ – pl,                                     (2)Ż = pl + ζR – αSZ,Ṙ = αSZ – ζR.26Wojciech TomczykSIZRQIn this model we add a quarantine class which contains members of the infec-ted or zombie population (entering at rates κ and σ, respectively). Those mem-bers are bound to be hospitalized under the threat of being eradicated if some-thing goes wrong. When a quarantined patient is cured, he or she once again becomes susceptible (parameter ω). The scheme is presented in Figure 4.Figure 4. SIZRQ modelSource: Own work.The equations describing SIZRQ model are:Ṡ = –βSZ + ωQ,İ = βSZ – ρI – κI,Ż = ρI + ζR – αSZ – σZ,                             (3)Ṙ = αSZ – ζR,Q̇ = κI + σZ – ωQ. 27Do Not Let the Dead Bite! Different Scenarios of the Zombie...SIZRQUIn contradiction to the SIZRQ model, when a quarantined patient is cured, he or she becomes immune to the ”zombie virus” forever (parameter γ). This can only happen after being exposed to contact with a zombie. Preventative vaccin- ation will not make someone permanently immune. The scheme is presented in Figure 5.Figure 5. SIZRQU modelSource: Own work.The equations describing SIZRQU model are:Ṡ = –βSZ,İ = βSZ – ρI – κI,Ż = ρI + ζR – αSZ – σZ,                              (4)Ṙ = αSZ – ζR,Q̇ = κI + σZ – γQ,U̇ = γQ.28Wojciech TomczykRESULTSTable 1 shows the values of the used parameters. The initial population of susceptibles was set to 1000, zombies to 1 and the rest to 0 (see section Mod- els). Numerical calculations were done in Mathematica 10.311.Table 1. Parameters and their values for adopted “toy” modelsParameter Valueα 0.007β 0.008γ 0.3ζ 0.8κ 0.05ρ 0.7σ 0.1ω 0.45As one can see, a state with only an outgoing arrow will always have popula-tion 0 at t → ∞. Furthermore, a state with only an ingoing arrow is an absorbing state (like U in Figure 5).SZRThe Zombie class overtakes the Removed after three days. The entire human population is eradicated (Figure 6) within four days.11 Wolfram Research, Inc., Mathematica, version 10.3, Champaign, IL (2015).29Do Not Let the Dead Bite! Different Scenarios of the Zombie...Figure 6. Numerical results for SZR modelSource: Own workSIZRThe Zombie apocalypse occurs after ten days. The Infected and Removed class survive up to the fifteenth day. Eventually everyone is zombified (Figure 7). Figure 7. Numerical results for SIZR modelSource: Own work.30Wojciech TomczykSIZRQIn this scenario the infected and zombified entities are quarantined at a fixed rate. We assume that it is always a successful venture and no one, who is hos- pitalized, ends in Removed class. However, those who are cured are becoming once again susceptibles. For this model as for the SIZR model the tenth day appears to be critical turning point. After thirty days, equilibrium is established between all classes (Figure 8 and 9). Data are shown in Table 2.Figure 8. Numerical results for SIZRQ modelSource: Own work.Figure 9. Magnification of part of Figure 8Source: Own work.31Do Not Let the Dead Bite! Different Scenarios of the Zombie...Table 2. Equilibrium state for all classes in SIZRQ modelClass Population valueZombies 659Quarantine 157Infected 94Removed 77Susceptibles 14SIZRQUAfter ten days the population of immune people starts to grow. Henceforth there are no susceptibles and the Infected and Removed class start to decrease. Eighty days are enough to immunize people and get rid of all zombies (Figure 10 and 11).Figure 10. Numerical results for SIZRQU model – SIR partSource: Own work.32Wojciech TomczykFigure 11. Numerical results for SIZRQU model – SZQU partSource: Own work.CONCLUSIONSIn summary, humans in mostly all presented scenarios are overwhelmed by zombies, except for one where a miraculous vaccine makes people immune to the “zombie virus”. That means, that before the zombie outbreak, we have to support the development of vaccinations.BIBLIOGRAPHY1. Alemi A. A., Bierbaum M., Myers C. R., Sethna J. P., You Can Run, You Can Hide: The Epidemiology and Statistical Mechanics of Zombies, “Physical Review E” 2015, No. 92.2. Booth W., Voodoo Science, “Science” 1988, No. 240. 3. Calderhead D., Girolami M., Higham D. J., Is It Safe to Go Out Yet? Statistical Inference in a Zombie Outbreak Model, “Department of Mathematics and Statistics Research Report” 2010, No. 6.4. Crisite D., Lauro S. J., Better Off Dead: The Evolution of the Zombie as Post-Human, New York 2011.5. Crossley M., Amos M., SimZombie: A Case-Study in Agent-Based Simulation Con-struction, “Agent and Multi-Agent Systems: Technologies and Applications Lecture Notes in Computer Science” 2011, No. 6682.6. Edmonds E. B., Gonzalez M. A., Caribbean Religious History: An Introduction, New York 2010.Do Not Let the Dead Bite! Different Scenarios of the Zombie...7. Kermack W. O., McKendrick A. G., A Contribution to the Mathematical Theory of Epidemics, “Proceedings of the Royal Society A: Mathematical, Physical and Engin- eering Sciences” 1927, No. 115 (772). 8. List of Zombies Films, [Online] https://en.wikipedia.org/wiki/List_of_zombie_films [accessed: 8.12.2015].9. Mogk M., Everything You Ever Wanted to Know About Zombies, New York 2011.10. Munz P., Hudea I., Imad J., Smith R. J., When Zombies Attack!: Mathematical Model-ling of An Outbreak of Zombie Infection, [in:] Infectious Disease Modelling Research Progress, eds. J. M. Tchuenche, C. Chiyaka, Ottawa 2011.11. Smith T. C., Zombie Infections: Epidemiology, Treatment, and Prevention, “The British Medical Journal” 2015, No. 351:h6423, DOI: 10.1136/bmj.h6423.12. Smith? R., Mathematical Modelling of Zombies, Ottawa 2013.13. Teschl G., Ordinary Differential Equations and Dynamical Systems, “Graduate Studies in Mathematics” 2012, No. 140.14. Wolfram Research, Inc., Mathematica, version 10.3, Champaign, IL (2015).

Do not let the dead bite! : different scenarios of the zombie epidemic reexamined

The Zombie Epidemic is a fun framework for investigating different scenarios of spreading disease. An extended Kermack – McKendrick model is analyzed. The only thing that can save humanity is to not get bitten or to find a remedy for the ”zombie virus” (both almost impossible)

Do not let the dead bite! : different scenarios of the zombie epidemic reexamined

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Do not let the dead bite! : different scenarios of the zombie epidemic reexamined

Abstract

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Jagiellonian Univeristy Repository

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