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Prevention of neuromuscular blockade: A proposal

Abstract

The purpose of this proposed study is to expand research on the prevention of postoperative residual neuromuscular blockade and examine the necessity of objective monitors. The researchers hypothesize that there will be an association with decrease in residual neuromuscular blockade and a set protocol for reversal. This is a proposal for a single blinded, prospective clinical trial comparing a control group with a protocol using medications and monitoring devices available at the majority of facilities in the United States. In the control group, accleromyographic data will be obtained upon entry to the post anesthesia care unit with no specific protocol present. In the experimental group, the set protocol will implemented and again acceleromyographic data will be obtained. These two data sets will be compared. A decrease in residual neuromuscular blockade in the experimental group will imply that a protocol for reversal is effective in preventing neuromuscular blockade and would question the necessity of objective monitoring. If there is no difference between the experimental and control group, this research would support other research that indicates a need for objective monitoring

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