Very-low-carbohydrate diets or ketogenic diets have been used 1920s to treat Epilepsy. Ultimately it finished medication. They have become widely known as one of the most common methods for obesity treatment. Now work over the last few years their therapeutic potential in many conditions, such as diabetes, polycystic ovary syndrome, acne, neurological diseases, cancer and the amelioration of respiratory and cardiovascular disease risk factors have been of help. The possibility that modifying food intake can be useful for reducing or eliminating medicinal treatment, which are often lifelong with significant side effects. It calls for serious investigation. Meaning of physiological ketosis in the light of this evidence is considered possible mechanisms for the therapeutic actions of the ketogenic diet on different diseases. There are still some well understood ideas about ketogenic diets, which may remove superfluous thinking. It could prove to be a boon later