Durante, M.

La Tessa, C.

Piersanti, L.

Rovituso, M.

Schuy, C.

GSI Repository

Fragmentation of therapeutical carbon ions in bone-like materialsM. Rovituso1,2,3, C. La Tessa1, L. Piersanti4,5, C. Schuy1, and M. Durante1,61GSI, Darmstadt, Germany; 2INFN Laboratori Nazionali del Sud, Catania, Italy; 3University of Catania, Italy;4University ”Sapienza” of Rome, Italy; 5INFN Laboratori Nazionali di Frascati, Italy; 6TU Darmstadt, GermanyHeavy-ion beams offer favourable conditions for thetherapy of cancer diseases. The type of tumors treated withsuch method is still limited but increasing. An importantstep for widening and improving its application is to char-acterize the interaction of the primary ions with speciﬁcmaterial, like bones, which are encountered by the primaryradiation before reaching the tumor.This work focuses on the characterization of nuclear in-teraction processes occurring when carbon ions in the ther-apeutical energy range transverse bone-like materials. Inthe measurements, 200 and 400 MeV/u 12C beams inter-acted with compact bone targets (Gammex RMI 450) ofdifferent thickness (1, 3 and 5 cm). For each beam energyand target thickness, the yield and kinetic energy spectraof neutral and charged particles were acquired at 0, 2.5, 5,10, 15, 20 and 30 degrees with respect to the primary beamdirection.The experimentA scheme of the experimental setup is shown in Fig. 1.Two plastic scintillators of 2 and 9 mm thickness (STARTand VETO, respectively), and a 14 cm long barium ﬂuoridescintillator (BaF2) were used.Figure 1: Scheme of the experimental setup.The identiﬁcation of the primary ions surviving the tar-get as well as of the secondary particles produced by frag-mentation of the former with the target nuclei was achievedwith deposited energy (ΔE) and residual energy (E) mea-sured with the VETO-BaF2 telescope. Once a particlespecies is selected, the kinetic energy spectrum are ob-tained from the Time-Of-Flight (TOF) data measured be-tween the START and BaF2 detectors.An example of a 2D plot of the ΔE and E signals col-lected with the telescope is shown in Fig 2.Figure 2: ΔE-E plot for a 200 MeV/u 12C beam interact-ing with 3 cm compact bone at 5 deg with respect to theprimary beam direction.The trend of the particle yield as a function of the angleis shown in Fig 3.Figure 3: Angular distributions of particles measured atforward angles from -2.5◦ to 30◦ for a 400 MeV/u 12C in-teracting with 5 cm compact bone target.The angular distributions are all forward peaked. Pri-mary ions and heavy fragments down to Li are detected inthe range from 0 to 10 deg and cannot be found at largerangles. Neutrons, helium and hydrogen fragments presenta different shape of the distribution, broader for the latter(hydrogen particles and neutrons) than for the former.GSI SCIENTIFIC REPORT 2012 HEALTH-63487

Fragmentation of therapeutical carbon ions in bone-like materials

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Fragmentation of therapeutical carbon ions in bone-like materials

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