International audienceHere we develop from a long term field experiment an assessment method of interstitial fauna resilience to combined sewer overflows (CSOs) effect. We address the case of small water courses for which the ratio of CSOs to natural flow can be 1 to much more. Biotic material was collected in the benthic and hyporheic layers. Biotic material focussed mainly on oligocheates species whose diversity, species category and abundance are resumed into metrics, called functional traits (FTrs), giving indications on flux dynamics and nutrient bio-assimilation capacity. The biotic resilience is assessed through the analysis of the response time of the biota to CSOs and natural flow characteristics, here called hydrological indices (HIs). In this aim, a series of hydrological indices are defined to reveal varying aspects of the dynamics of CSOs and natural flows. A main result is that CSOs can have both degrading and boosting effects on the biota of a stony stream. Some CSOs characteristics can explain the physical processes supporting these contrasting effects. In particular the geomorphic characteristics of the water course. Management perspectives emerge from the CSOs hydrological indices and resilience of the biota