PDF file 79K, Supplementary Figure S1: Uptake of imatinib and OCT1 probe substrate TEA into OCT1-expressing cells and vector-transfected control cells Supplementary Figure S2: Cellular uptake of the OCT1 probe substrate TEA and imatinib into mOct1- or mOct2-expressing HEK293 cells Supplementary Figure S3: Cellular uptake of imatinib into the CML cell lines Meg-01, LAMA-84 and K562 as well as into OCT1-expressing HEK cells and vector-transfected control cells measured after an incubation period of 120 minutes Supplementary Figure S4: Cellular uptake of imatinib into HEK cells expressing variant V408 in comparison to HEK cells expressing reference sequence M408 and vector-transfected control cells measured after an incubation period of 10 minutes Supplementary Figure S5: Knockdown of OCT1 protein expression by the used shRNA</p
