Background and Objective: Anti tuberculosis drugs therapy is the most effective method for controling
the tuberculosis (TB). Early detection and appropriate treatment can prevent the TB-drug resistance. This
study was carried out to determine the complications leading to hospitalization due to consumption of
anti-TB drugs in patients with tuberculosis.
Methods: In this descriptive-analytic study, 1550 records of patients with TB in urban and rural health
centers of Gorgan, north of Iran were assessed during 2007-12. Checklist consists of demographic and
clinical data for each patient was recorded in a questionare.
Results: 44 cases experienced the complications of anti-TB drugs. 27 (61.4%) of cases with
complications were women. 77.3% and 22.7% of patients affected with pulmonary and extra pulmonary
tuberculosis,respectively. 38.6% of patients were diabetic. The hepatic complication was seen in 37 cases
(84.1%). Skin and other complications were seen in 5 and 2 cases, respectively. There was not any
relationship between drug complications and other disases.
Conclusion: Hepatic damage is the most common complication leading to hospitalization in tuberculosis
patients using anti-TB drugs.
Keywords: Tuberculosis, Anti-TB drug, Live
