(A) UMAP dimensional reduction plot of scRNA-seq data with cells labeled by their assigned unsupervised cluster (resolution = 0.05). (B) Bar plot depicting the number of chimpanzee and human cells assigned to each cluster. (C) Violin plots displaying the distribution of UMI counts per cell for each cluster. (D) Violin plots displaying the distribution of gene counts per cell for each cluster. (E) The correlation of average gene expression patterns between technical replicates (human and chimpanzee) collected in each cluster. (F-H) Enrichment of GO functional categories in marker genes for iPSC.c1 (F), MSC.c1 (G), and Osteogenic.c1 (H). The top 5 GO functions identified in biological processes (BP), cell components (CC), and molecular functions (MF) are displayed along with the adjusted p-value (p-adjust), the number of marker genes overlapping a GO function (Count), and the ratio of overlapping to non-overlapping marker genes for a given GO function (Gene Ratio). (TIF)</p
