Orally administered liposomal bovine lactoferrin (LbLF) suppressed inflammation in diseased leg joints at 15 weeks after mannan injection.

Abstract

Leg joint histology. In the arthritis (Ar) group, prominent pannus proliferation (b, f) was observed, and the joint cartilage layer was completely destroyed (j) comparing to those in the control (Cont) (a, e, i). LbLF100 (c, g, k) and LbLF500 (d, h, l) application alleviated pannus formation and cartilage destruction.</p