Growth curve and the percentages of GFP-positive parasites.

Abstract

(A) Infected red blood cells (1 x 106) of transgenic parasites (PvCEN11S2, PvCEN11S2-H86HD-TG; PvCEN11S3, PvCEN11S3-H86HD-TG; PyCEN5, PyCEN5-H86HD-TG; and pNoCEN) or the parental parasite (17XL) were inoculated into each mouse and maintained with pyrimethamine except 17XL. Parasitemias were determined daily until day 7. (B) The percentage of GFP-positive parasites without pyrimethamine was examined at 7 time points until day 28. Mean and standard deviation from 5 mice were plotted for each group.</p