The Rete algorithm is a well-known algorithm in rule-based production systems
which builds directed acyclic graphs that represent higher-level rule sets. This allows
the rule-based systems to avoid complete re-evaluation of all conditions of the rules each
step in order to check the applicability of the rules and, therefore, the computational
e ciency of the production systems is improved. In this paper we study how these ideas
can be applied in the improvement of the design of computational simulators in the
framework of Membrane Computing.Junta de Andalucía P08-TIC-04200Ministerio de Economía y Competitividad TIN2012-3743