Biochemical and histological analyses of 1MP.I mice.

Abstract

(A–C) The graphs indicate the biochemical results for serum Ca, P, and 1–84 PTH concentrations for control mice (white bar, n = 15) and 1MP.I mice (black bar, n = 14) (U-test, P > 0.05). (D, E) Histology of the parathyroid gland of control mice (D) and 1MP.I mice (E) stained with hematoxylin and eosin. Yellow arrowhead (E) indicates acinar structures surrounded by cells in the parathyroid glands. (F–K) In situ hybridization of Gcm2 (F and I), Pth (G and J), and Casr (H and K) in the parathyroid gland of control mice (F–H) and 1MP.I mice (I–K). All scale bars were 100 μm.</p