Abedi, Vida

Bassaganya-Riera, Josep

Ciupe, Stanca M

Erwin, Samantha

Hontecillas-Magarzo, Raquel

Hoops, Stefan

Verma, Meghna

VCU Scholars Compass

Virginia Commonwealth UniversityVCU Scholars CompassBiology and Medicine Through MathematicsConference 2016May 21st, 5:00 PM - 5:20 PMMathematical models of HIV and HPV coinfectionSamantha ErwinVirginia Polytechnic Institute and State University, sherwin@vt.eduMeghna VermaVirginia Polytechnic Institute and State UniversityVida AbediVirginia Polytechnic Institute and State UniversitySee next page for additional authorsFollow this and additional works at: http://scholarscompass.vcu.edu/bammPart of the Immunology of Infectious Disease Commons, Medical Biomathematics andBiometrics Commons, Ordinary Differential Equations and Applied Dynamics Commons, and theVirus Diseases CommonsThis Event is brought to you for free and open access by the Dept. of Mathematics and Applied Mathematics at VCU Scholars Compass. It has beenaccepted for inclusion in Biology and Medicine Through Mathematics Conference by an authorized administrator of VCU Scholars Compass. Formore information, please contact libcompass@vcu.edu.http://scholarscompass.vcu.edu/bamm/2016/May21/56Presenter InformationSamantha Erwin, Meghna Verma, Vida Abedi, Raquel Hontecillas-Magarzo, Stefan Hoops, Josep Bassaganya-Riera, and Stanca M. CiupeThis event is available at VCU Scholars Compass: http://scholarscompass.vcu.edu/bamm/2016/May21/56 Mathematical models of HIV and HPV coinfection.  HIV infected patients have an increased incidence of chronic HPV infection, leading to precancerous cells. To address the effect of HIV on HPV pathogenesis, we develop a mathematical model of HIV-HPV coinfection that captures known interactions such as decreased HPV-specific cytotoxic T cells and increased HPV viral production. From our mathematical analysis, we predict biological conditions under which coinfected individuals can clear HPV. We address the clinical implications of anti-retroviral therapy used to treat HIV in HPV-coinfected patients and compare it to previous clinical observations.  

Mathematical models of HIV and HPV coinfection

http://scholarscompass.vcu.edu/cgi/viewcontent.cgi?article=1010&context=bamm

Mathematical models of HIV and HPV coinfection

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