The definition of diabetes control varies widely among specialists of the disease. Proponents of good control believe that the goals of appropriate therapy for diabetes should include an all-out effort to obtain levels of fasting and postprandial blood glucose as close to those in the non-diabetic as possible. Certainly, good control has been proven to accomplish the following: 1. prevention of ketoacidosis; 2. prevention of severe hypoglycemia; 3. decrease in perinatal mortality and morbidity; 4. promotion of normal growth and development of the juvenile diabetic; 5. prevention of, or inhibition of, infection. The evidence that hyperglycemia is responsible for vascular complications, particularly micro-vascular disease, and that good control will prevent or inhibit the rapidity of the development of this pathologic process, or even reverse it, is the basis of this presentation