The concept of office endometrial sampling is not new. Kelly recommended its use in 1925. More recently, the procedure has received increased attention as physicians and the public have sought ways to curb the spiraling cost of medical care. Uterine curettage is the operation most commonly performed on women throughout the world. As an inpatient procedure, it costs 500to600. The same procedure performed in an outpatient surgical center costs 350to400. In over 90% of cases, an adequate endometrial sample may be obtained in the office at a cost of 50to60. For office endometrial sampling to be acceptable to the physician, it must be simple to accomplish, relatively inexpensive to use, and agreeable in terms of patient comfort and morbidity. The specimen obtained should be representative of the entire endometrium, adequate for pathological study, and easily preserved, transported, and processed
