<i>Scube3^{+/tm1(KOMP)Vlcg}</i> reporter gene activity at E10.5 visualized by β-galactosidase staining.

Abstract

<p>(A) Lateral view; (B) Frontal view (of the craniofacial region); (C) Posterior view. Note reporter expression in the central nervous system and ectoderm of the facial processes, otic vesicle and limb buds. Strong posterior-restricted expression is also seen in the limb bud mesenchyme <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0055274#pone.0055274-Xavier1" target="_blank">[13]</a> (only visible in the hindlimb of this sample). dd, dorsal dermomyotome; flb, forelimb bud; hb, hindbrain; hlb, hindlimb budlb, limb bud; mb, midbrain; md, mandibular process; mx, maxillary process; oe, oral ectoderm; ov, otic vesicle; pa2, pharyngeal arch 2; rh, rhombencephalon; vd, ventral dermomyotome.</p