Effects of evodiamine (EVO) on the cell cycle distribution and apoptosis rate of the H446 and H1688 SCLC cells.

Abstract

<p>Cell cycle was detected by PI assay. Apoptosis was detected using an Annexin V/PI double staining assay. The H446 cells stained with Annexin V/PI were observed under an inverted fluorescence microscope. Each experiment was repeated 3 times. Data presented as mean ± standard deviation (n = 3). *<i>P</i><0.05 as compared to corresponding control group. Untreated H446 or H1688 cells were used as a negative control group.</p