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尺寸均一、高活性保持的壳聚糖载药微球的制备
Authors
王连艳
苏志国
马光辉
魏炜
Publication date
1 January 2006
Publisher
Abstract
<正>随着生物技术的发展,越来越多的多肽和蛋白质类药物应用于疾病的预防和治疗中,但是多肽和蛋白质在体内的循环半衰期短,单独用药时容易被体内的酶类所降解,需要频繁注射给药, 这不仅给病人带来痛苦和不便,而且体内血药浓度波动大容易引起毒副作用。而壳聚糖载药微球因其具有粘附性和缓控释作用,可以提高药物在体内的生物利用度,同时通过对药物的缓、控
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Last time updated on 09/11/2016