Urticaria has been known from antiquity. The disorder was
known to the Arabs as essera and it has found a place in the
writings of Cesius (circa 30 BC–45 AD). Although the condition
was recognised as an entity, its cause was a mystery to the
physicians of those times. It was initially thought to be a
manifestation of idiosyncrasy and later believed to be a form
of neuroses. However, now the pathophysiological basis of
urticaria is well understood. The development of antihistamine
group of drugs, paved the way for the management of urticaria
