Little is known whether intensive training and a highly-procedural environment can alleviate the influence of personality on decision making. Here, we address this issue by investigating the influence of impulsivity as personality factor on decision making among airline pilots. We showed that impulsivity modulated pilots’ indecisiveness in uncertain decision scenarios as well as pilots’ self-reported compliance to airline guidelines in real life. This result suggests that the personality factor impulsivity is a profound trait that continues to have an influence through intensive training and highly-procedural decision situations