The pyogenic Granuloma is a focal reactive injury, not neoplasic, of fibrobascular tissue or granulation. Feminine sexual hormones influence its ethiopatogeny and when it occurs during pregnancy it is called gravidic pyogenic granuloma or pregnancy tumor. During gestation, this injury can present a rapid and accelerated growth, acquiring dimensions that interfere with chewing, affecting nutrition and consequently fetus development. Gravidic pyogenic granuloma is located more frequently in the front vestibular gum in the upper maxillary. However, its presence has also been reported at an extra gingival level. This case report describes the clinical, radiographic, histopathologic characteristics and the treatment of an unusual extra gingival located gravidic pyogenic granuloma, in the edentate alveolar locking lip of a 22 year-old patient in post pregnancy period.The pyogenic Granuloma is a focal reactive injury, not neoplasic, of fibrobascular tissue or granulation.Feminine sexual hormones influence its ethiopatogeny and when it occurs during pregnancy it is calledgravidic pyogenic granuloma or pregnancy tumor. During gestation, this injury can present a rapidand accelerated growth, acquiring dimensions that interfere with chewing, affecting nutrition and consequentlyfetus development. Gravidic pyogenic granuloma is located more frequently in the front vestibulargum in the upper maxillary. However, its presence has also been reported at an extra gingival level.This case report describes the clinical, radiographic, histopathologic characteristics and the treatment ofan unusual extra gingival located gravidic pyogenic granuloma, in the edentate alveolar locking lip of a22 year-old patient in post pregnancy period.Key Words: gravidic pyogenic granuloma, hormonal changes, pregnancy. El granuloma piogénico es una lesión reactiva focal, no neoplásica, de tejido fibrovascular o de granulación. Las hormonas sexuales femeninas influyen en su etiopatogenia y cuando ocurre durante el embarazo es llamado granuloma piogénico gravídico o tumor del embarazo. Durante la gestación esta lesión puede presentar un crecimiento rápido y exagerado, adquiriendo dimensiones que interfieren con la masticación, afectando la nutrición y en consecuencia el desarrollo fetal. El granuloma piogénico gravídico se localiza con mayor frecuencia en la encía vestibular anterior del maxilar superior. Sin embargo, también se ha reportado su presencia a nivel extragingival. Este reporte de caso describe las características clínicas, radiográficas, histopatológicas y el tratamiento de un granuloma piogénico gravídico de localizión extragingival inusual, en el reborde alveolar edéntulo de una paciente de 22 años de edad en período postparto
