Objective: to evaluate the epidemiological profile of gestational and congenital toxoplasmosis in extreme poverty municipalities in Brazil from 2019 to 2022. Methods: this is an ecological study based on secondary data from the Information Technology Department of the Unified Health System (DATASUS). Information was collected on the number of notified cases of gestational and congenital toxoplasmosis, considering extreme poverty municipalities as the place of residence. The variables evaluated were region and race for gestational toxoplasmosis, age group, schooling, congenital toxoplasmosis, and gender. Results: between 2019 and 2022, 6,895 new cases of Gestational Toxoplasmosis (GT) and 1,677 new cases of Congenital Toxoplasmosis (CT) were reported in extreme poverty municipalities in Brazil. In terms of the country's regions, the highest number of cases was concentrated in the Northeast during the period analyzed. Regarding cases by race, black people were the only ones with a statistically significant upward trend in both diseases. Analyzing cases by sex in CT, there was a percentage increase in both sexes, but with high statistical significance in females. As for the age group in GT, women aged between 20 and 39 showed a significant upward trend. Conclusion: based on the analysis of the data, the absolute numbers point to a significant increase in cases, especially in 2022.Objetivo: Evaluar el perfil epidemiológico de la toxoplasmosis gestacional y congénita en municipios de extrema pobreza de Brasil de 2019 a 2022. Métodos: Se trata de un estudio ecológico basado en datos secundarios del Departamento de Informática del Sistema Único de Salud (DATASUS). Se recopiló información sobre el número de casos notificados de toxoplasmosis gestacional y congénita, considerando como lugar de residencia los municipios de extrema pobreza. Las variables evaluadas fueron región y raza, para toxoplasmosis gestacional, grupo de edad y escolaridad, y toxoplasmosis congénita, sexo. Resultados: Entre 2019 y 2022, se notificaron 6.895 casos nuevos de toxoplasmosis gestacional (GT) y 1.677 casos nuevos de toxoplasmosis congénita (CT) en municipios de extrema pobreza de Brasil. En cuanto a las regiones del país, el mayor número de casos se concentró en el Nordeste durante el período analizado. En cuanto a los casos por raza, las personas negras fueron las únicas con una tendencia ascendente estadísticamente significativa en ambas enfermedades. Analizando los casos por sexo en CT, se observó un incremento porcentual en ambos sexos, pero con alta significación estadística en el sexo femenino. En cuanto al grupo de edad en GT, las mujeres de entre 20 y 39 años mostraron una importante tendencia al alza. Conclusión: Con base en el análisis de los datos, los números absolutos apuntan a un aumento significativo de casos, especialmente en 2022.Objective: to evaluate the epidemiological profile of gestational and congenital toxoplasmosis in extreme poverty municipalities in Brazil from 2019 to 2022. Methods: this is an ecological study based on secondary data from the Information Technology Department of the Unified Health System (DATASUS). Information was collected on the number of notified cases of gestational and congenital toxoplasmosis, considering extreme poverty municipalities as the place of residence. The variables evaluated were region and race for gestational toxoplasmosis, age group, schooling, congenital toxoplasmosis, and gender. Results: between 2019 and 2022, 6,895 new cases of Gestational Toxoplasmosis (GT) and 1,677 new cases of Congenital Toxoplasmosis (CT) were reported in extreme poverty municipalities in Brazil. In terms of the country's regions, the highest number of cases was concentrated in the Northeast during the period analyzed. Regarding cases by race, black people were the only ones with a statistically significant upward trend in both diseases. Analyzing cases by sex in CT, there was a percentage increase in both sexes, but with high statistical significance in females. As for the age group in GT, women aged between 20 and 39 showed a significant upward trend. Conclusion: based on the analysis of the data, the absolute numbers point to a significant increase in cases, especially in 2022