Burr, David B.

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295J Musculoskelet Neuronal Interact 2007; 7(4):295-296The 37th International Sun Valley Workshop on Skeletal Tissue Biology was held August 5-8, 2007. There were 93 Workshopattendees representing a wide range of clinical, basic science and social science disciplines. The W.S.S. Jee Remodeling in Bone (RIB) Award was given to Dr. David Baylink, who spoke about "The IGF System in theRise and Fall in Bone Density with Age". This presentation generated lively discussion, and comments made by Dr. Baylink aboutIGF were revisited throughout the Workshop. The plenary lecture was followed by a poster session that highlighted posters fromthe eleven young investigators who received the Alice L. Jee Memorial Travel Award. The Workshop program was also high-lighted by podium talks on Monday evening from six young investigators who were selected winners of the ASBMR/HaroldM. Frost Young Investigator Awards, which came with a $1,500 prize (supported in part by the ASBMR) and certificate. Besides training, a primary focus of the Workshop has been on the interaction of younger and more senior investigators. Forthe 38th Workshop next year (2008), we will expand the mentorship program established at the 30th Workshop in 2000. Thisprogram requires the younger scientists who have received awards to share lunch with a senior investigator of their choice. Thelunches at the Sun Valley lodge are paid for by the Workshop to allow for this exchange. In 2008, we will expand this to thoseyoung investigators who express a desire (at the time of registration) for such interaction with senior investigators. We expectto provide as many as 35 vouchers for mentor luncheons.At the 37th Workshop, sessions were presented on Primary Cilia (Chris Jacobs, Chair), Dmp1 and Phosphate Regulation(Charles Turner and Anne George, Chairs), Tissue Engineering (Robert Guldberg and Kevin Healey, Chairs), Aging and Os-teoporosis (Steve Cummings, Chair) and Osteonecrosis and ONJ (Harry Kim, Chair). Again, in keeping with our desire to pro-vide content especially for the younger investigators, Dr. Nancy Lane presented information on the US Bone and Joint Decade’sinitiatives for Young Investigators. For those who were unable to attend this year, this information can be found on the US Boneand Joint Decade website: www.usbjd.org.The Workshop was supported by grants from the National Institutes of Health (NIAMS, NIDCR and NICHD) and the Or-thopaedic Research and Education Foundation (OREF). In addition, contributions from industry came from pharmaceuticalconcerns (Alliance for Better Bone Health; Amgen; Eli Lilly and Co.; Pfizer Global Research and Development; Wyeth-Ayerst Pharmaceuticals; Merck); contract research companies (MDS Pharma Services, Charles River Laboratories) and man-ufacturers of imaging and diagnostic equipment and services (Immunodiagnostic Systems Inc., Micro Photonics Inc., Osteometrics;and Scanco USA, Inc).The 38th International Sun Valley Workshop will be held August 3-6, 2008, and will expand into areas of musculoskeletal bi-ology beyond bone, including Chondrocyte Biology and Muscle Biology. Additional sessions are planned for The Genetics ofOsteoporosis, Nanomechanics of Bone, and Bone as an Endocrine Organ. We are excited to announce that Dr. Lance Lanyonwill receive the W.S.S. Jee Remodeling in Bone (RIB) Award for his long-standing contributions to our understanding of bonebiology and to the interface between bone mechanics and biology. Dr. Lanyon will give the plenary lecture.Finally, we are planning an NIH Workshop on Funding for Young Investigators in 2008. This workshop will be presented byrepresentatives from the National Institute of Arthritis, Musculoskeletal and Skin Diseases, and promises to be of significantvalue not just to the younger investigators whom it targets, but even to those veterans who may want some handy tips to im-prove their scores in this age of increasing competitiveness. These are all important reasons to attend the Workshop in 2008. We hope to see you there!David B. Burr, PhDOrganizer and Director37th International Sun Valley Workshop on Skeletal Tissue BiologyAssociate Editor of JMNIThe 37th International Sun Valley Workshop on Skeletal Tissue BiologyForeword The 37th International Sun Valley Workshop on Skeletal Tissue Biology296Sunday Morning (8 am-Noon)Primary Cilia(Chair: Chris Jacobs)1. The primary cilium: What once did nothing, now doeseverything - Tim Stearns, Stanford University2. Shaping up and shipping out - Jill Helms, Stanford Uni-versity3. Primary cilia in bone - Chris Jacobs, Stanford University4. Intraflagellar transport in skeletal development - Rosa Serra,University of AlabamaSunday Evening (7:30 pm-10 pm)RIB Award/Plenary SessionThe Role of IGF System in the Rise and Fall in Bone Densitywith Age (David Baylink, Loma Linda University)[Poster Viewing followed the Plenary Session]Monday Morning (8 am-Noon)DMP1 and Phosphate Regulation(Co-Chairs: Charles Turner and Anne George)1. DMP1 - a key regulator in mineralized matrix formation- Anne George, University of Illinois, Chicago2. Use of the transgenic approach to determine the role ofDMP1 in phosphate regulation - Jerry Feng, Baylor Schoolof Dentistry 3. The role of DMP1 in autosomal recessive hypophos-phatemic rickets - Ken White, Indiana University4. DMP1 and MEPE expression are elevated in osteocytes af-ter mechanical stimulation in vivo: Theoretical role in con-tolling mineral quality in the perilacunar matrix - Steve Har-ris, University of Texas, San AntonioPresentation on the US Bone and Joint Decade/Young InvestigatorsWorkshop - Nancy Lane, UC DavisMonday Evening (7:30 pm-10 pm) Presentations by ASBMR/Harold M. Frost Award Recipients 1. Heritability of lumbar trabecular bone mechanical prop-erties in baboons - Lorena Havill, Southwest Foundationfor Biomedical Research2. A homozygous missense mutation in human KLOTHOcauses severe tumoral calcinosis - Shoji Ichikawa, Indi-ana University3. Pericyte/myofibroblast phenotype of osteoprogenitor cell- Ivo Kalajzic, University of Connecticut Health Center4. Ror2, a novel modulator of osteogenesis - Yan Liu, WyethResearch 5. A chemical and engineering approach towards "smart" syn-thetic bone grafts - Jie Song, University of Massachusetts 6. ATF4 is a key molecule linking food intake and skeletal de-velopment - Hideaki Sowa, Columbia University Tuesday Morning (8 am-Noon)Tissue Engineering(Chairs: Kevin Healy and Robert Guldberg)1. Gene therapy strategies for craniofacial tissue engineering- Paul Krebsbach, University of Michigan2. Biointerfaces promoting tissue healing - Andres Garcia,Georgia Institute of Technology3. Biologic augmentation of polymer scaffolds for bone re-pair - Robert Guldberg, Georgia Institute of Technology4. Extracellular matrix elasticity directs stem cell differenti-ation - Adam Engler, Princeton University5. Designer biomaterials: Too much information? - KevinHealy, UC BerkeleyWednesday Morning (8 am-Noon)Aging and Osteoporosis(Chair: Steve Cummings)1. The (brief) epidemiology and biology of aging - SteveCummings, San Francisco Coordinating Center2. Aging and fragility of bone - Charles Turner, IndianaUniversity3. Aging and sarcopenia - David Thompson, Pfizer GlobalResearch & Development 4. Vascular calcification - Linda Demer, University of CA,Los Angeles 5. Aging and falls: Causes and prevention - Steve Lord,Prince of Wales Medical Research Institute, AustraliaWednesday Evening (7:30 pm-10 pm)Osteonecrosis ONJ(Chair: Harry Kim)1. Introduction to osteonecrosis of the femoral head (OFH)and osteonecrosis of the jaw ONJ) - Harry Kim, ShrinersHospital, Tampa2. Summary of ASBMR Task Force on ONJ - David Burr,Indiana University3. Distinguishing features of the oral cavity and its predis-position to osteonecrosis - Laurie McCauley, Universityof Michigan4. Animal models of osteonecrosis of the jaw - Matt Allen,Indiana University37th International Sun Valley Workshop On Skeletal Tissue BiologyAugust 5-8, 2007, Sun Valley, Idaho, USA

The 37th International Sun Valley Workshop on Skeletal Tissue Biology: Foreword

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The 37th International Sun Valley Workshop on Skeletal Tissue Biology: Foreword

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