Pemphigus Vulgaris : case report

Abstract

Case report on a 53yr old gentleman who initially presented to his family doctor with mouth ulcers, hoarseness and odynophagia. He was given various treatments including antibiotics, anti-virals, non-steroidal anti-inflammatory drugs (NSAIDs) and oral steroids with no effect. His condition worsened and was associated with a 5kg weight loss. He subsequently developed skin blisters and erosions and was referred to the dermatology department. A clinical diagnosis of pemphigus vulgaris was made and he was started on high dose oral steroids. A skin biopsy sent for histology and immunofluorescence confirmed the diagnosis. On confirmation he was admitted for rituximab therapy and started on azathioprine.peer-reviewe