Impact on outcome following to thrombolytic therapy in acute myocardial infarction and left bundle branch block

Abstract

Background: Prompt diagnosis of Acute Myocardial Infarction (AMI) and Left Bundle Branch Block (LBBB) is a clinical challenge, as massive anteroseptal myocardial infarctions occur in the background of left bundle branch block. Selection of the patients for thrombolytic therapy is debatable. Materials and Methods: The study is conducted in Al-Ameen Medical College Hospital, Bijapur in the period from December 2011 to September 2013. 45 patients with left bundle branch block and acute myocardial Infarction are included in the study, 25 patients received thrombolytic therapy, 20 patients have not received and are observed for a period of 28 days. Design of the study is hospital based randomized control trial. Results: In 25 patients subjected for thrombolytic therapy, 1 (2.2%) died during the hospital stay and in 20 patients who did not receive thrombolytic therapy, 5 patients (11.1%) died during hospital stay. Conclusion: Thrombolytic therapy is proved to be beneficial and if denied are at high risk for acute complications like Arrhythmias, Cardiac arrest